Overview

  • Product nameAnti-HSD17B7 antibody
    See all HSD17B7 primary antibodies
  • Description
    Rabbit polyclonal to HSD17B7
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 160-209 (SDNPSQLIWT SSRSARKSNF SLEDFQHSKG KEPYSSSKYA TDLLSVALNR) of Human HSD17B7 (NP_057455).

  • Positive control
    • PANC1 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab122995 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionResponsible for the reduction of the keto group on the C-3 of sterols.
  • Tissue specificityHighly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. Isoform 3 is expressed in eye ciliary epithelial cells and neuroendocrine cells.
  • PathwaySteroid biosynthesis; estrogen biosynthesis.
    Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 5/6.
  • Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 17 beta HSD 7 antibody
    • 17 beta hydroxysteroid dehydrogenase 7 antibody
    • 17 beta hydroxysteroid dehydrogenase type VII antibody
    • 17-beta-HSD 7 antibody
    • 17-beta-hydroxysteroid dehydrogenase 7 antibody
    • 17beta hydroxysteroid dehydrogenase antibody
    • 3 keto steroid reductase antibody
    • 3-keto-steroid reductase antibody
    • DHB7_HUMAN antibody
    • Estradiol 17 beta dehydrogenase 7 antibody
    • Estradiol 17-beta-dehydrogenase 7 antibody
    • Hsd17b7 antibody
    • Hydroxysteroid (17 beta) dehydrogenase 7 antibody
    • MGC12523 antibody
    • MGC75018 antibody
    • PRAP antibody
    • SDR37C1 antibody
    • Short chain dehydrogenase/reductase family 37C member 1 antibody
    see all

Anti-HSD17B7 antibody images

  • Anti-HSD17B7 antibody (ab122995) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size : 38 kDa

References for Anti-HSD17B7 antibody (ab122995)

ab122995 has not yet been referenced specifically in any publications.

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