Overview

  • Product nameAnti-HSD17B7 antibody
    See all HSD17B7 primary antibodies
  • Description
    Mouse polyclonal to HSD17B7
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    HSD17B7 (NP_057455.1, 1 a.a. ~ 341 a.a) full-length human protein.

  • Positive control
    • HSD17B7 transfected 293T lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab69341 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 30 kDa (predicted molecular weight: 39 kDa).

Target

  • FunctionResponsible for the reduction of the keto group on the C-3 of sterols.
  • Tissue specificityHighly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. Isoform 3 is expressed in eye ciliary epithelial cells and neuroendocrine cells.
  • PathwaySteroid biosynthesis; estrogen biosynthesis.
    Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 5/6.
  • Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 17 beta HSD 7 antibody
    • 17 beta hydroxysteroid dehydrogenase 7 antibody
    • 17 beta hydroxysteroid dehydrogenase type VII antibody
    • 17-beta-HSD 7 antibody
    • 17-beta-hydroxysteroid dehydrogenase 7 antibody
    • 17beta hydroxysteroid dehydrogenase antibody
    • 3 keto steroid reductase antibody
    • 3-keto-steroid reductase antibody
    • DHB7_HUMAN antibody
    • Estradiol 17 beta dehydrogenase 7 antibody
    • Estradiol 17-beta-dehydrogenase 7 antibody
    • Hsd17b7 antibody
    • Hydroxysteroid (17 beta) dehydrogenase 7 antibody
    • MGC12523 antibody
    • MGC75018 antibody
    • PRAP antibody
    • SDR37C1 antibody
    • Short chain dehydrogenase/reductase family 37C member 1 antibody
    see all

Anti-HSD17B7 antibody images

  • All lanes : Anti-HSD17B7 antibody (ab69341) at 1/500 dilution

    Lane 1 : HSD17B7 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 39 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)

References for Anti-HSD17B7 antibody (ab69341)

ab69341 has not yet been referenced specifically in any publications.

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