Overview

  • Product nameAnti-HSD17B8 antibody
    See all HSD17B8 primary antibodies
  • Description
    Rabbit polyclonal to HSD17B8
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 51-100 (TVRLLGGPGS KEGPPRGNHA AFQADVSEAR AARCLLEQVQ ACFSRPPSVV) of Human HSD17B8 (NP_055049).

  • Positive control
    • RPMI-8226 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab123005 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionNAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.
  • Tissue specificityHighly expressed in placenta, liver and pancreas, lower in the skeletal muscle and kidney. Widely expressed.
  • PathwaySteroid biosynthesis; estrogen biosynthesis.
    Lipid metabolism; fatty acid biosynthesis.
  • Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localizationMitochondrion matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • 17 beta HSD 8 antibody
    • 17 beta hydroxysteroid dehydrogenase 8 antibody
    • 17-beta-HSD 8 antibody
    • 17-beta-hydroxysteroid dehydrogenase 8 antibody
    • 17-beta-hydroxysteroid dehydrogenase VIII antibody
    • 3-oxoacyl-[acyl-carrier-protein] reductase antibody
    • 3-oxoacyl-acyl-carrier protein reductase, E. coli, homolog of antibody
    • Beta ketoacyl [acyl carrier protein] reductase like antibody
    • D6S2245E antibody
    • DHB8_HUMAN antibody
    • dJ1033B10.9 antibody
    • Estradiol 17 beta dehydrogenase 8 antibody
    • Estradiol 17-beta-dehydrogenase 8 antibody
    • Estrogen 17 oxidoreductase antibody
    • FABG antibody
    • FabG, E. coli, homolog of antibody
    • FabG-like antibody
    • FABGL antibody
    • H2 KE6 antibody
    • H2-KE6 antibody
    • HKE6 antibody
    • HSD17B8 antibody
    • Hydroxysteroid (17 beta) dehydrogenase 8 antibody
    • Ke-6 antibody
    • KE6 antibody
    • KE6, mouse homolog of antibody
    • Protein Ke6 antibody
    • Really interesting new gene 2 protein antibody
    • RING2 antibody
    • SDR30C1 antibody
    • Short chain dehydrogenase/reductase family 30C member 1 antibody
    • Testosterone 17 beta dehydrogenase 8 antibody
    • Testosterone 17-beta-dehydrogenase 8 antibody
    see all

Anti-HSD17B8 antibody images

  • Anti-HSD17B8 antibody (ab123005) at 1 µg/ml + RPMI-8226 cell lysate at 10 µg

    Predicted band size : 26 kDa

References for Anti-HSD17B8 antibody (ab123005)

ab123005 has not yet been referenced specifically in any publications.

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