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Rabbit monoclonal [EPR12084(B)] to HSD17B8
IP more details Unsuitable for:
Flow Cyt or IHC-P
Synthetic peptide corresponding to amino acid residues in Human HSD17B8 (Q92506).
Human fetal liver, HepG2, BxPC-3 and JAR cell lysates. JAR cells.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab ® patents
This product is a recombinant rabbit monoclonal antibody.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/250.
1/10000 - 1/50000. Predicted molecular weight: 26 kDa.
1/10 - 1/100.
Is unsuitable for Flow Cyt or IHC-P.
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.
Highly expressed in placenta, liver and pancreas, lower in the skeletal muscle and kidney. Widely expressed.
Steroid biosynthesis; estrogen biosynthesis.
Lipid metabolism; fatty acid biosynthesis.
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Information by UniProt
17 beta HSD 8 antibody
17 beta hydroxysteroid dehydrogenase 8 antibody
17-beta-HSD 8 antibody
Immunocytochemistry/ Immunofluorescence - Anti-HSD17B8 antibody [EPR12084(B)] (ab169752)
Immunofluorescent analysis of JAR cells labelling HSD17B8 with ab169752 at 1/100 dilution.
Western blot - Anti-HSD17B8 antibody [EPR12084(B)] (ab169752)
All lanes : Anti-HSD17B8 antibody [EPR12084(B)] (ab169752) at 1/10000 dilution Lane 1 : Fetal liver lysate Lane 2 : HepG2 lysate Lane 3 : Bx-PC-3 lysate Lane 4 : JAR lysate Lysates/proteins at 10 µg per lane. Predicted band size: 26 kDa
Immunoprecipitation - Anti-HSD17B8 antibody [EPR12084(B)] (ab169752)
Western blot analysis on immunoprecipitation pellet from (1) fetal liver lysate labeling HSD17B8 with ab169752 at 1/10 dilution or (2) 1X PBS (negative control. HRP-conjugated anti-rabbit IgG preferentially detected the non-reduced form of Rabbit IgG.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"