Overview

  • Product nameAnti-HSD3a antibody
    See all HSD3a primary antibodies
  • Description
    Mouse monoclonal to HSD3a
  • Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-324 of Human HSD3a

Properties

Applications

Our Abpromise guarantee covers the use of ab54606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 37 kDa.
IHC-P Use a concentration of 3 µg/ml.
ICC/IF Use a concentration of 15 µg/ml.

Target

  • FunctionCatalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
  • Tissue specificityLiver specific.
  • Sequence similaritiesBelongs to the aldo/keto reductase family.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3 alpha HSD1 antibody
    • 3-alpha-HSD1 antibody
    • 3-alpha-hydroxysteroid dehydrogenase type I antibody
    • AK1C4_HUMAN antibody
    • AKR1C4 antibody
    • Aldo keto reductase family 1 member C4 antibody
    • Aldo-keto reductase family 1 member C4 antibody
    • CDR antibody
    • Chlordecone reductase antibody
    • DD-4 antibody
    • DD4 antibody
    • Dihydrodiol dehydrogenase 4 antibody
    • HAKRA antibody
    see all

Anti-HSD3a antibody images

  • HSD3a antibody (ab54606) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human liver tissue.


  • Predicted band size : 37 kDa
    HSD3a antibody (ab54606) at 1ug/lane + MCF-7 cell lysate at 25ug/lane.
  • ab54606 at 15 µg/ml staining HSD3a in human HepG2 cells by Immunocytochemistry / Immunofluorescence.

References for Anti-HSD3a antibody (ab54606)

ab54606 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"