Overview

  • Product name
  • Description
    Goat polyclonal to HSH2D
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide:

    C-HSHVGYTLSYKAQ

    , corresponding to internal sequence amino acids 62-74 of Human HSH2D (NP_116244.1).

  • Positive control
    • K-562 cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab101039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 39 kDa.

Target

  • Function
    May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter.
  • Tissue specificity
    Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta.
  • Sequence similarities
    Contains 1 SH2 domain.
  • Post-translational
    modifications
    May be phosphorylated by FES and ACK1.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adaptor in lymphocytes of unknown function X antibody
    • ALX antibody
    • FLJ14886 antibody
    • hematopoietic SH2 domain containing antibody
    • Hematopoietic SH2 domain containing protein antibody
    • Hematopoietic SH2 domain-containing protein antibody
    • Hematopoietic SH2 protein antibody
    • HSH2 antibody
    • Hsh2d antibody
    • HSH2D_HUMAN antibody
    see all

Images

  • Anti-HSH2D antibody (ab101039) at 0.3 µg/ml + K-562 Cell Lysate (in RIPA buffer) at 35 µg

    Predicted band size : 39 kDa

References

ab101039 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab101039.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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