Overview

  • Product name
  • Description
    Mouse polyclonal to HSH2D
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein corresponding to amino acids 1-352 of Human HSH2D. (AAH25237).

  • Positive control
    • HSH2D transfected 293T cell lysate. HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab169172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa.
ICC/IF Use a concentration of 10 µg/ml.

Target

  • Function
    May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter.
  • Tissue specificity
    Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta.
  • Sequence similarities
    Contains 1 SH2 domain.
  • Post-translational
    modifications
    May be phosphorylated by FES and ACK1.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adaptor in lymphocytes of unknown function X antibody
    • ALX antibody
    • FLJ14886 antibody
    • hematopoietic SH2 domain containing antibody
    • Hematopoietic SH2 domain containing protein antibody
    • Hematopoietic SH2 domain-containing protein antibody
    • Hematopoietic SH2 protein antibody
    • HSH2 antibody
    • Hsh2d antibody
    • HSH2D_HUMAN antibody
    see all

Images

  • All lanes : Anti-HSH2D antibody (ab169172) at 1 µg/ml

    Lane 1 : HSH2D transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Secondary
    Goat anti-mouse HRP at 1/2500 dilution

    Predicted band size : 39 kDa
  • Immunocytochemistry/Immunofluorescence analysis of HeLa cells labeling HSH2D with ab169172 at 10µg/ml.

References

ab169172 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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