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Product name Anti-Hsp105 antibody See all Hsp105 primary antibodies
Rabbit polyclonal to Hsp105
Tested applications Suitable for:
WB, IP more details
Mouse, Rat, Human
Synthetic peptide corresponding to N terminus of mouse Hsp105.
Western Blotting- Hela cell lysate.
Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, 1.0% BSA, PBS
Concentration information loading...
Purity Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 105 kDa (predicted molecular weight: 97 kDa).
Use a concentration of 10 - 20 µg/ml.
Function Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
Tissue specificity Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Sequence similarities Belongs to the heat shock protein 70 family.
Post-translational modifications Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
Cellular localization Cytoplasm.
Information by UniProt
Antigen NY CO 25 antibody
Antigen NY-CO-25 antibody
Anti-Hsp105 antibody images
References for Anti-Hsp105 antibody (ab24503)
This product has been referenced in:
The Mammalian disaggregase machinery: hsp110 synergizes with hsp70 and hsp40 to catalyze protein disaggregation and reactivation in a cell-free system. PLoS One 6:e26319 (2011).
Read more (PubMed: 22022600) »
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for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"