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Rabbit polyclonal to Hsp105 - C-terminal
Synthetic peptide, corresponding to the C terminal of Human Hsp105 (NP_006635.2).
- Human pancreas tissue; HeLa cell extract; HeLa cells.
Shipped at 4°C. Store at -20°C.
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
Note: without Mg2+, Ca2+
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/500 - 1/1000. Predicted molecular weight: 96 kDa.
||Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
||1/100 - 1/500.
Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Belongs to the heat shock protein 70 family.
Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
Information by UniProt
- Antigen NY CO 25 antibody
- Antigen NY-CO-25 antibody
- DKFZp686M05240 antibody
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Hsp105 antibody - C-terminal (ab166780)
Immunohistochemical analysis of formalin-fixed,
paraffin-embedded Human pancreas tissue labeling Hsp105 with ab166780 at 5 µg/ml.
Western blot - Anti-Hsp105 antibody - C-terminal (ab166780)
All lanes : Anti-Hsp105 antibody - C-terminal (ab166780) at 1/500 dilution
Lane 1 : HeLa cell extract
Lane 2 : HeLa cell extract with synthesized peptide
Predicted band size: 96 kDa
Immunocytochemistry/ Immunofluorescence - Anti-Hsp105 antibody - C-terminal (ab166780)
Immunofluorescent analysis of HeLa cells labeling Hsp105 with ab166780 at 1/100 dilution. The image on the right is treated with the synthesized peptide.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"