• Product nameAnti-Hsp60 antibody [LK 1]
    See all Hsp60 primary antibodies
  • Description
    Mouse monoclonal [LK 1] to Hsp60
  • SpecificityThis antibody is specific to the 60 kDa protein, HSP60. This antibody recognizes only mammalian HSP60 and not bacterial HSP60.
  • Tested applicationsSuitable for: ICC/IF, IHC-P, IHC-Fr, IP, WBmore details
  • Species reactivity
    Reacts with: Rat, Chicken, Hamster, Human
    Does not react with: Escherichia coli
  • Immunogen

    BALB/C mice were injected with recombinant HSP 60 protein.

  • Positive control
    • Breast carcinoma



Our Abpromise guarantee covers the use of ab1819 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
IHC-P 1/25 - 1/75. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. PubMed: 16947118ABC method.
IHC-Fr 1/25 - 1/75. ABC method.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration.


  • FunctionImplicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
  • Involvement in diseaseDefects in HSPD1 are a cause of spastic paraplegia autosomal dominant type 13 (SPG13) [MIM:605280]. Spastic paraplegia is a degenerative spinal cord disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs.
    Defects in HSPD1 are the cause of leukodystrophy hypomyelinating type 4 (HLD4) [MIM:612233]; also called mitochondrial HSP60 chaperonopathy or MitCHAP-60 disease. HLD4 is a severe autosomal recessive hypomyelinating leukodystrophy. Clinically characterized by infantile-onset rotary nystagmus, progressive spastic paraplegia, neurologic regression, motor impairment, profound mental retardation. Death usually occurrs within the first two decades of life.
  • Sequence similaritiesBelongs to the chaperonin (HSP60) family.
  • Cellular localizationMitochondrion matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • 60 kDa chaperonin antibody
    • 60 kDa heat shock protein, mitochondrial antibody
    • CH60_HUMAN antibody
    • Chaperonin 60 antibody
    • Chaperonin, 60-KD antibody
    • CPN60 antibody
    • fa04a05 antibody
    • GROEL antibody
    • heat shock 60kDa protein 1 (chaperonin) antibody
    • Heat shock protein 1 (chaperonin) antibody
    • Heat shock protein 60 antibody
    • Heat shock protein 65 antibody
    • heat shock protein family D (Hsp60) member 1 antibody
    • HLD4 antibody
    • Hsp 60 antibody
    • HSP 65 antibody
    • HSP-60 antibody
    • HSP60 antibody
    • HSP65 antibody
    • HSPD1 antibody
    • HuCHA60 antibody
    • Mitochondrial matrix protein P1 antibody
    • P60 lymphocyte protein antibody
    • short heat shock protein 60 Hsp60s1 antibody
    • SPG13 antibody
    see all

Anti-Hsp60 antibody [LK 1] images

  • ab1819 staining human breast carcinoma by IHC-P.

References for Anti-Hsp60 antibody [LK 1] (ab1819)

This product has been referenced in:
  • Bellingham M  et al. Exposure to chemical cocktails before or after conception - the effect of timing on ovarian development. Mol Cell Endocrinol 376:156-72 (2013). IHC . Read more (PubMed: 23791816) »
  • Fowler PA  et al. Gene expression analysis of human fetal ovarian primordial follicle formation. J Clin Endocrinol Metab 94:1427-35 (2009). IHC ; Human . Read more (PubMed: 19258411) »

See all 4 Publications for this product

Product Wall

Thank you very much for the feedback that you have provided. It would be most helpful if you could submit your results and protocol information as a review: go to the online datasheet for ab1819, click on the reviews tab, and then click on add a review...

Read More

approx. 100 ug/ml