Overview

  • Product nameAnti-Hsp70 antibodySee all Hsp70 primary antibodies ...
  • Description
    Rabbit polyclonal to Hsp70
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Sheep, Rabbit, Chicken, Guinea pig, Hamster, Cow, Dog, Human, Pig, Fruit fly (Drosophila melanogaster), Fish, Monkey
  • Immunogen

    Synthetic peptide derived from the sequence of rat Hsp70

  • Positive control
    • Heat shocked 3T3 cell lysate
  • General notesConcentration: See product label

Properties

Applications

Our Abpromise guarantee covers the use of ab69412 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1 ug/ml. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionIn cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
    • Tissue specificityHSPA1B is testis-specific.
    • Sequence similaritiesBelongs to the heat shock protein 70 family.
    • Cellular localizationCytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
    • Information by UniProt
    • Database links
    • Alternative names
      • Constitutive heat shock protein 70 antibody
      • dnaK type molecular chaperone HSP70 1 antibody
      • FLJ54303 antibody
      • FLJ54370 antibody
      • FLJ54392 antibody
      • FLJ54408 antibody
      • FLJ75127 antibody
      • Heat shock 70 kDa protein 1 antibody
      • Heat shock 70 kDa protein 1/2 antibody
      • Heat shock 70 kDa protein 1A/1B antibody
      • Heat shock 70kD protein 1 antibody
      • Heat shock 70kD protein 10 (HSC71) antibody
      • Heat shock 70kD protein 8 (HSP73) antibody
      • Heat shock 70kDa protein 1A antibody
      • Heat shock 70kDa protein 1B antibody
      • Heat shock cognate 71 kDa protein antibody
      • Heat shock induced protein antibody
      • HSP70 1 antibody
      • HSP70 1/HSP70 2 antibody
      • HSP70 2 antibody
      • HSP70-1/HSP70-2 antibody
      • HSP70-1A antibody
      • HSP70.1 antibody
      • HSP70.1/HSP70.2 antibody
      • HSP70I antibody
      • HSP71_HUMAN antibody
      • HSP72 antibody
      • HSPA1 antibody
      • HSPA1A antibody
      • HSPA1B antibody
      • N myristoyltransferase inhibitor protein 71 antibody
      • NIP71 antibody
      • Uncharacterized bone marrow protein BM034 antibody
      see all

    Anti-Hsp70 antibody images

    • All lanes : Anti-Hsp70 antibody (ab69412) at 1 µg/ml

      Lane 1 : Mouse 3T3 cell lysate
      Lane 2 : Heat shocked 3T3 cell lysate
      Lane 3 : Purified Hsp70 protein
      Lane 4 : Purified Hsc70 protein

      developed using the ECL technique

      Predicted band size : 71 kDa
      Observed band size : 71 kDa

    References for Anti-Hsp70 antibody (ab69412)

    This product has been referenced in:
    • Cooper TK  et al. Use of urinary biomarkers of renal ischemia in a lamb preclinical left ventricular assist device model. Artif Organs 36:820-4 (2012). Sheep . Read more (PubMed: 22428807) »

    See 1 Publication for this product

    Product Wall

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"