Overview

  • Product nameAnti-Hsp70 antibodySee all Hsp70 primary antibodies ...
  • Description
    Rabbit polyclonal to Hsp70
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human, Fish
    Predicted to work with: Mouse, Rat, Chicken, Cow, Fruit fly (Drosophila melanogaster)
  • Immunogen

    Synthetic peptide sequence conserved in all known Hsp70 and Hsc70 proteins.

  • Positive control
    • Wet plant sample extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab80177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB 1/1000 - 1/10000. Detects a band of approximately 70 kDa (predicted molecular weight: 71 kDa). (0.1 µl/ml was sufficient to detect Hsp70/Hsc70 in 1 mg wet plant extract).

Target

  • FunctionIn cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
  • Tissue specificityHSPA1B is testis-specific.
  • Sequence similaritiesBelongs to the heat shock protein 70 family.
  • Cellular localizationCytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Target information above from: UniProt accession P08107 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • Constitutive heat shock protein 70 antibody
    • dnaK type molecular chaperone HSP70 1 antibody
    • FLJ54303 antibody
    • FLJ54370 antibody
    • FLJ54392 antibody
    • FLJ54408 antibody
    • FLJ75127 antibody
    • Heat shock 70 kDa protein 1 antibody
    • Heat shock 70 kDa protein 1/2 antibody
    • Heat shock 70 kDa protein 1A/1B antibody
    • Heat shock 70kD protein 1 antibody
    • Heat shock 70kD protein 10 (HSC71) antibody
    • Heat shock 70kD protein 8 (HSP73) antibody
    • Heat shock 70kDa protein 1A antibody
    • Heat shock 70kDa protein 1B antibody
    • Heat shock cognate 71 kDa protein antibody
    • Heat shock induced protein antibody
    • HSP70 1 antibody
    • HSP70 1/HSP70 2 antibody
    • HSP70 2 antibody
    • HSP70-1/HSP70-2 antibody
    • HSP70-1A antibody
    • HSP70.1 antibody
    • HSP70.1/HSP70.2 antibody
    • HSP70I antibody
    • HSP71_HUMAN antibody
    • HSP72 antibody
    • HSPA1 antibody
    • HSPA1A antibody
    • HSPA1B antibody
    • Lipopolysaccharide associated protein 1 antibody
    • LPS associated protein 1 antibody
    • MGC131511 antibody
    • MGC29929 antibody
    • N myristoyltransferase inhibitor protein 71 antibody
    • NIP71 antibody
    • Uncharacterized bone marrow protein BM034 antibody
    see all

Anti-Hsp70 antibody images

  • All lanes : Anti-Hsp70 antibody (ab80177) at 1/1000 dilution

    Lane 1 : Lysates prepared from rat tissue
    Lane 2 : Lysates prepared from human tissue


    Predicted band size : 71 kDa

References for Anti-Hsp70 antibody (ab80177)

ab80177 has not yet been referenced specifically in any publications.

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