Overview

  • Product nameAnti-Hsp70 antibody [C96F3-3]
    See all Hsp70 primary antibodies
  • Description
    Mouse monoclonal [C96F3-3] to Hsp70
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Cow, Human
    Predicted to work with: Fish
  • Immunogen

    Native Human Hsp70.

  • Positive control
    • HeLa Cell Lysate, Heat Shocked; 3T3 Cell Lysate; PC-12 Cell Lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab115651 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 70 kDa (predicted molecular weight: 70 kDa). (ECL).

Target

  • FunctionIn cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
  • Tissue specificityHSPA1B is testis-specific.
  • Sequence similaritiesBelongs to the heat shock protein 70 family.
  • Cellular localizationCytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt
  • Database links
  • Alternative names
    • DnaK type molecular chaperone HSP70 1 antibody
    • Epididymis secretory protein Li 103 antibody
    • FLJ54303 antibody
    • FLJ54370 antibody
    • FLJ54392 antibody
    • FLJ54408 antibody
    • FLJ75127 antibody
    • Heat shock 70 kDa protein 1 antibody
    • Heat shock 70 kDa protein 1/2 antibody
    • Heat shock 70 kDa protein 1A/1B antibody
    • Heat shock 70kDa protein 1A antibody
    • Heat shock 70kDa protein 1B antibody
    • Heat shock induced protein antibody
    • HEL S 103 antibody
    • HSP70 1 antibody
    • HSP70 1B antibody
    • HSP70 2 antibody
    • HSP70-1/HSP70-2 antibody
    • HSP70-1A antibody
    • HSP70.1 antibody
    • HSP70.1/HSP70.2 antibody
    • HSP70I antibody
    • HSP71_HUMAN antibody
    • HSP72 antibody
    • HSPA1 antibody
    • HSPA1A antibody
    • HSPA1B antibody
    see all

Anti-Hsp70 antibody [C96F3-3] images

  • All lanes : Anti-Hsp70 antibody [C96F3-3] (ab115651) at 1/1000 dilution

    Lane 1 : HSP70 Recombinant Human Protein
    Lane 2 : HSP70B’ Recombinant Human Protein
    Lane 3 : HSP70-A1 Recombinant Mouse Protein
    Lane 4 : HSP70 Recombinant Chinook Salmon Protein
    Lane 5 : HSC70 Recombinant Bovine Protein
    Lane 6 : HSC70 (ATPase Fragment) Recombinant Bovine Protein
    Lane 7 : HeLa Cell Lysate
    Lane 8 : HeLa Cell Lysate, Heat Shocked
    Lane 9 : 3T3 Cell Lysate
    Lane 10 : 3T3 Cell Lysate, Heat Shocked
    Lane 11 : PC-12 Cell Lysate
    Lane 12 : PC-12 Cell Lysate, Heat Shocked


    Predicted band size : 70 kDa

References for Anti-Hsp70 antibody [C96F3-3] (ab115651)

ab115651 has not yet been referenced specifically in any publications.

Product Wall

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