Anti-Hsp90 beta antibody, prediluted (ab54266)

Overview

  • Product nameAnti-Hsp90 beta antibody, prediluted
    See all Hsp90 beta primary antibodies
  • Description
    Rabbit polyclonal to Hsp90 beta, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Cow, Cynomolgus Monkey, Asian Toad (Bufo)
  • Immunogen

    Synthetic peptide:

    PEEVHHGEEEVE

    , corresponding to N terminal amino acids 2-13 of Mouse Hsp90 beta

  • Positive control
    • MAD109 cells or breast carcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab54266 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    Working dilution: Ready-to-use for 30 min at RT
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
    The optimal dilution for a specific application should be determined by the investigator.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMolecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
    • Sequence similaritiesBelongs to the heat shock protein 90 family.
    • DomainThe TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins.
    • Post-translational
      modifications
      Ubiquitinated in the presence of STUB1-UBE2D1 complex (in vitro).
      ISGylated.
      S-nitrosylated; negatively regulates the ATPase activity.
    • Cellular localizationCytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • Database links
    • Alternative names
      • 90 kda heat shock protein beta HSP90 beta antibody
      • D6S182 antibody
      • FLJ26984 antibody
      • Heat shock 84 kDa antibody
      • Heat shock 90kD protein 1, beta antibody
      • Heat shock 90kDa protein 1 beta antibody
      • Heat shock protein 90kDa alpha (cytosolic) class B member 1 antibody
      • Heat shock protein beta antibody
      • Heat shock protein HSP 90 beta antibody
      • Heat shock protein HSP 90-beta antibody
      • HS90B_HUMAN antibody
      • HSP 84 antibody
      • HSP 90 antibody
      • HSP 90 b antibody
      • HSP 90b antibody
      • HSP84 antibody
      • HSP90 BETA antibody
      • hsp90ab1 antibody
      • HSP90B antibody
      • HSPC2 antibody
      • HSPCB antibody
      see all

    Anti-Hsp90 beta antibody, prediluted images

    • Human breast carcinoma stained with anti-Hsp90 beta (ab54266)

    References for Anti-Hsp90 beta antibody, prediluted (ab54266)

    ab54266 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"