Overview

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab40009 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    Blocking - Blocking peptide for Anti-Hsp90 antibody (ab19021)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Thimerosal (merthiolate)
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • Heat shock 86 kDa
    • Heat shock protein 90kDa alpha cytosolic class A member 1
    • Heat shock protein 90kDa alpha cytosolic class B member 1
    • Heat shock protein HSP 90 alpha
    • Heat shock protein HSP 90 beta
    • Heat shock protein HSP 90-alpha
    • HS90A_HUMAN
    • HSP 84
    • HSP 86
    • Hsp 90
    • HSP86
    • HSP90A
    • HSP90AA1
    • HSP90AB1
    • HSP90B
    • HSPC1
    • HSPC2
    • HSPCAL1
    • HSPCAL4
    • Renal carcinoma antigen NY-REN-38
    see all
  • FunctionMolecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
  • Sequence similaritiesBelongs to the heat shock protein 90 family.
  • DomainThe TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins like the co-chaperone STUB1.
  • Post-translational
    modifications
    ISGylated.
    S-nitrosylated; negatively regulates the ATPase activity and the activation of eNOS by HSP90AA1.
  • Cellular localizationCytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

References for Hsp90 peptide (ab40009)

ab40009 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab40009.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"