Overview

  • Product nameAnti-HSPC152 antibody
    See all HSPC152 primary antibodies
  • Description
    Mouse monoclonal to HSPC152
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-126 of Human HSPC152

Properties

Applications

Our Abpromise guarantee covers the use of ab57156 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionParticipates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species.
    • Sequence similaritiesBelongs to the TRM112 family.
      Contains 1 TRM112 domain.
    • Information by UniProt
    • Database links
    • Alternative names
      • HSPC152 antibody
      • HSPC170 antibody
      • HSPC170 protein antibody
      • Hypothetical protein HSPC152 antibody
      • Hypothetical protein LOC51504 antibody
      • TR112_HUMAN antibody
      • TRM112 antibody
      • TRM112 like protein antibody
      • TRM112-like protein antibody
      • TRMT11 2 antibody
      • Trmt112 antibody
      • tRNA methyltransferase 11-2 homolog (S. cerevisiae) antibody
      • tRNA methyltransferase 112 homolog antibody
      see all

    Anti-HSPC152 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57156 HSPC152 antibody at 1ug/ml. Predicted band size of immunogen is 40 kDa

    References for Anti-HSPC152 antibody (ab57156)

    This product has been referenced in:
    • Fu D  et al. Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival. Mol Cell Biol 30:2449-59 (2010). WB ; Human . Read more (PubMed: 20308323) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"