Anti-HSV1 + HSV2 gD antibody [12.6] (ab41198)

Overview

  • Product nameAnti-HSV1 + HSV2 gD antibody [12.6]
    See all HSV1 + HSV2 gD primary antibodies
  • Description
    Mouse monoclonal [12.6] to HSV1 + HSV2 gD
  • Specificityab41198 recognises HSV1 + HSV2 gD.
  • Tested applicationsSuitable for: ICC/IF, ELISAmore details
  • Species reactivity
    Reacts with HSV1 + HSV2. Not yet tested in other species.
  • Immunogen

    Tissue/ cell preparation: HSV1 + HSV2 gD

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number12.6
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab41198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent dilution.
ELISA 1/1600.

Target

  • RelevanceHerpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two species of the herpes virus family, Herpesviridae, which cause infections in humans. They are also called Human Herpes Virus 1 and 2 (HHV-1 and HHV-2) and are neurotropic and neuroinvasive viruses; they enter and hide in the human nervous system, accounting for their durability in the human body. Under a microscope, HSV- 1 and 2 are virtually identical, sharing approximately 50% of their DNA. Both types infect the body's mucosal surfaces, usually the mouth or genitals, and then establish latency in the nervous system. HSV-1 is commonly associated with herpes outbreaks of the face known as cold sores or fever blisters, whereas HSV-2 is more often associated with genital herpes. Herpes simplex viruses (HSV) use multiple and sequential receptors to enter host cells. HSV glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.
  • Alternative names
    • Envelope glycoprotein D antibody
    • GD antibody
    • Glycoprotein D antibody
    • US6 antibody

References for Anti-HSV1 + HSV2 gD antibody [12.6] (ab41198)

ab41198 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"