Anti-HSV1 gD antibody [1-I-9] (ab18638)
Key features and details
- Mouse monoclonal [1-I-9] to HSV1 gD
- Suitable for: ELISA, WB
- Reacts with: Herpes simplex virus
- Isotype: IgG1
Overview
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Product name
Anti-HSV1 gD antibody [1-I-9] -
Description
Mouse monoclonal [1-I-9] to HSV1 gD -
Host species
Mouse -
Tested applications
Suitable for: ELISA, WBmore details -
Species reactivity
Reacts with: Herpes simplex virus -
Immunogen
Tissue, cells or virus corresponding to HSV1 gD. HSV1 viral concentrate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
1-I-9 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab18638 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent dilution.
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WB |
Use at an assay dependent dilution. Predicted molecular weight: 43 kDa.
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Notes |
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ELISA
Use at an assay dependent dilution. |
WB
Use at an assay dependent dilution. Predicted molecular weight: 43 kDa. |
Target
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Relevance
Herpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. Glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread. -
Database links
- Entrez Gene: 2703406 Herpes simplex virus
- SwissProt: Q69091 Herpes simplex virus
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Alternative names
- GD antibody
- Glycoprotein D antibody
- Herpes simplex virus type 1 glycoprotein D antibody
- HSV1 glycoprotein D antibody
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab18638 has been referenced in 2 publications.
- Bhattacharya I et al. Plasma Membrane-Derived Liposomes Exhibit Robust Antiviral Activity against HSV-1. Viruses 14:N/A (2022). PubMed: 35458528
- Brun P et al. Herpes Simplex Virus Type 1 Infects Enteric Neurons and Triggers Gut Dysfunction via Macrophage Recruitment. Front Cell Infect Microbiol 8:74 (2018). PubMed: 29600197