Anti-HSV1 gD antibody [1.3] (ab41197)

Overview

  • Product nameAnti-HSV1 gD antibody [1.3]
    See all HSV1 gD primary antibodies
  • Description
    Mouse monoclonal [1.3] to HSV1 gD
  • Specificityab41197 recognises HSV I gD.
  • Tested applicationsSuitable for: ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with HSV 1. Not yet tested in other species.
  • Immunogen

    Tissue/ cell preparation: HSV I and II infected cells.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferAzide free.
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number1.3
  • IsotypeIgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab41197 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1600.
ICC/IF Use at an assay dependent dilution.

Target

  • RelevanceHerpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. Glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.
  • Alternative names
    • GD antibody
    • Glycoprotein D antibody
    • Herpes simplex virus type 1 glycoprotein D antibody
    • HSV1 glycoprotein D antibody

References for Anti-HSV1 gD antibody [1.3] (ab41197)

ab41197 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"