Anti-HSV1 gE Envelope Protein antibody [9H3] (ab6510)
Key features and details
- Mouse monoclonal [9H3] to HSV1 gE Envelope Protein
- Suitable for: ELISA, ICC/IF, WB
- Reacts with: Herpes simplex virus
- Isotype: IgG2a
Overview
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Product name
Anti-HSV1 gE Envelope Protein antibody [9H3] -
Description
Mouse monoclonal [9H3] to HSV1 gE Envelope Protein -
Host species
Mouse -
Tested applications
Suitable for: ELISA, ICC/IF, WBmore details -
Species reactivity
Reacts with: Herpes simplex virus -
Immunogen
Tissue, cells or virus corresponding to HSV1 gE Envelope Protein.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.4 -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
9H3 -
Myeloma
NS1/1-Ag4-1 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab6510 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ELISA |
Use at an assay dependent concentration.
0.100 @ >1:102,400 |
|
ICC/IF |
1/6400.
1+ @ 1:6,400 |
|
WB |
Use at an assay dependent concentration. PubMed: 16571817
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Notes |
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ELISA
Use at an assay dependent concentration. 0.100 @ >1:102,400 |
ICC/IF
1/6400. 1+ @ 1:6,400 |
WB
Use at an assay dependent concentration. PubMed: 16571817 |
Target
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Relevance
There are 2 antigenic types of Herpes Simplex Virus, HSV1 and HSV2 which share antigenic cross reactivity but different neutralization patterns and tend to produce different clinical symptoms. Humans are believed to be the natural host for HSV, but the virus is also capable of infecting various animals, including rodents. -
Database links
- Entrez Gene: 2703448 Herpes simplex virus
- SwissProt: P04488 Herpes simplex virus
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Alternative names
- Envelope glycoprotein E antibody
- GE antibody
- Glycoprotein E antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (9)
ab6510 has been referenced in 9 publications.
- Qiao H et al. Cerebral Organoids for Modeling of HSV-1-Induced-Amyloid β Associated Neuropathology and Phenotypic Rescue. Int J Mol Sci 23:N/A (2022). PubMed: 35682661
- Denes CE et al. A putative WAVE regulatory complex (WRC) interacting receptor sequence (WIRS) in the cytoplasmic tail of HSV-1 gE does not function in WRC recruitment or neuronal transport. Access Microbiol 3:000206 (2021). PubMed: 34151161
- Qiao H et al. Herpes simplex virus type 1 infection leads to neurodevelopmental disorder-associated neuropathological changes. PLoS Pathog 16:e1008899 (2020). PubMed: 33091073
- Zhang W et al. Induction of Rod-Shaped Structures by Herpes Simplex Virus Glycoprotein I. J Virol 94:N/A (2020). PubMed: 32581097
- Dai HS et al. The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells. Immunity 47:159-170.e10 (2017). PubMed: 28723548
- Oda S et al. The Interaction between Herpes Simplex Virus 1 Tegument Proteins UL51 and UL14 and Its Role in Virion Morphogenesis. J Virol 90:8754-67 (2016). PubMed: 27440890
- Arii J et al. Nonmuscle myosin heavy chain IIb mediates herpes simplex virus 1 entry. J Virol 89:1879-88 (2015). PubMed: 25428876
- Maringer K et al. A network of protein interactions around the herpes simplex virus tegument protein VP22. J Virol 86:12971-82 (2012). IP . PubMed: 22993164
- Orlando JS et al. The products of the herpes simplex virus type 1 immediate-early US1/US1.5 genes downregulate levels of S-phase-specific cyclins and facilitate virus replication in S-phase Vero cells. J Virol 80:4005-16 (2006). WB . PubMed: 16571817