Overview

  • Product name
    Anti-HSV1+ HSV2 ICP27 antibody [H1113]
    See all HSV1+ HSV2 ICP27 primary antibodies
  • Description
    Mouse monoclonal [H1113] to HSV1+ HSV2 ICP27
  • Specificity
    ab53480m reacts with HSV1+ HSV2 ICP27.
  • Tested applications
    Suitable for: ICC/IF, WB, IPmore details
  • Species reactivity
    Reacts with: Herpes Simplex Virus
  • Immunogen

    HSV infected cell extract.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    H1113
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab53480 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 10 µg/ml. Predicted molecular weight: 55 kDa.
IP Use at an assay dependent dilution. PubMed: 19321610

Target

  • Relevance
    Herpes simplex virus (HSV) ICP27 (Infected cell polypeptide 27) is an essential and multifunctional regulator of viral gene expression that modulates RNA splicing, polyadenylation, and nuclear export. ICP27 Belongs to the herpesviruses UL69 family. It is involved in the down-regulation of viral immediate-early genes and acts in combination with ICP0 and ICP4 as an activator of late genes.
  • Alternative names
    • ICP47 protein antibody
    • Immediate early protein IE12 antibody
    • Infected cell protein 47 antibody
    • US12 antibody
    • US12 protein antibody
    see all

References

This product has been referenced in:
  • Souki SK  et al. Arginine methylation of the ICP27 RGG box regulates ICP27 export and is required for efficient herpes simplex virus 1 replication. J Virol 83:5309-20 (2009). WB, IP . Read more (PubMed: 19321610) »
  • Ackermann M  et al. Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodies. J Virol 52:108-18 (1984). Read more (PubMed: 6090689) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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