The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
RelevanceHerpes simplex virus (HSV) encodes four nuclear phosphoproteins that contribute towards the full productive lytic cycle cascade in newly infected permissive cells. The IE175 (or ICP4) and IE63 (or ICP27) proteins have essential regulatory roles during the lytic cycle. A third, IE110 (or ICP0), appears to play only an accessory role in the presence of VP16, but in the absence of VP16 appears to be critical for initiation of reactivated infections.
Alpha 0 protein antibody
Herpes siplex virus 1 antibody
HHV1 ICP0 antibody
HSV1 IE110 antibody
Human Herpesvirus 1 antibody
Immediate early nuclear phosphoprotein antibody
Immediate early protein IE110 antibody
Trans acting transcriptional protein ICP0 antibody
Anti-HSV1 ICP0 antibody [5H7] images
Immunocytochemistry/ Immunofluorescence - Anti-HSV1 ICP0 antibody [5H7] (ab6513)This image is courtesy of an anonymous Abreview
ab6513 (1/25600) staining HSV1 ICP0 in human cells. Cells were PFA-fixed, permeabilized in 0.3% TritonX-100/PBS and blocked in 1% serum /30 minutes /25oC. A fluorescently labeled donkey anti-mouse antibody was used as the secondary.
References for Anti-HSV1 ICP0 antibody [5H7] (ab6513)
This product has been referenced in:
Jurak I et al. Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity. J Virol86:10093-102 (2012).
Read more (PubMed: 22787211) »
Dufour F et al. The ribonucleotide reductase R1 subunits of herpes simplex virus 1 and 2 protect cells against poly(I · C)-induced apoptosis. J Virol85:8689-701 (2011).
Read more (PubMed: 21697465) »