Human AADACL1 full length protein (ab132863)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionQ6PIU2
    • SpeciesHuman
    • SequenceMRSSCVLLTALVALAAYYVYIPLPGSVSDPWKLMLLDATFRGAQQVSNLI HYLGLSHHLLALNFIIVSFGKKSAWSSAKVKVTDTDFDGVEVRVFEGPPK PEEPLKRSVVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLV PKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAAL GQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVK YWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNY KPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYIMTCEHDVL RDDGIMYAKRLESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSY IKWLDQNL
    • Molecular weight71 kDa including tags
    • Amino acids1 to 408

Specifications

Our Abpromise guarantee covers the use of ab132863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

    ELISA

  • FormLiquid
  • Additional NotesProtein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General info

  • Alternative names
    • Arylacetamide deacetylase like 1
    • Arylacetamide deacetylase-like 1
    • NCEH
    • Nceh1
    • NCEH1_HUMAN
    • Neutral cholesterol ester hydrolase
    • Neutral cholesterol ester hydrolase 1
    see all
  • FunctionHydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.
  • Tissue specificityExpressed in monocyte-derived macrophages. Up-regulated in invasive melanoma and breast carcinoma cell lines.
  • Sequence similaritiesBelongs to the 'GDXG' lipolytic enzyme family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationMembrane. Microsome.
  • Information by UniProt

Human AADACL1 full length protein images

  • 12.5% SDS-PAGE analysis of ab132863 stained with Coomassie Blue.

References for Human AADACL1 full length protein (ab132863)

ab132863 has not yet been referenced specifically in any publications.

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