Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab32269 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General info

  • Alternative names
    • 2' 5' oligoadenylate binding protein
    • 2''-5''-oligoadenylate-binding protein
    • 2'5' oligoadenylate binding protein
    • ABC 38
    • ABC 38
    • ABC38
    • ABC38
    • ABCE 1
    • ABCE 1
    • ABCE1
    • ABCE1_HUMAN
    • ATP binding cassette sub family E (OABP) member 1
    • ATP Binding Cassette Sub Family E Member 1
    • ATP Binding Cassette Sub Family E Member 1
    • ATP-binding cassette sub-family E member 1
    • HuHP 68
    • HuHP68
    • OABP
    • OABP
    • Ribonuclease 4 Inhibitor
    • Ribonuclease 4 Inhibitor
    • Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor
    • Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor
    • Ribonuclease L inhibitor
    • RLI
    • RLI
    • RNase L Inhibitor
    • RNase L Inhibitor
    • RNASEL1
    • RNASELI
    • RNS 4I
    • RNS4I
    • RNS4I
    see all
  • FunctionAntagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
  • Sequence similaritiesBelongs to the ABC transporter superfamily. ABCE family.
    Contains 2 4Fe-4S ferredoxin-type domains.
    Contains 2 ABC transporter domains.
  • Cellular localizationCytoplasm. Mitochondrion. Localized to clusters of virus formation at the plasma membrane.
  • Information by UniProt

References for Human ABCE1 peptide (ab32269)

ab32269 has not yet been referenced specifically in any publications.

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