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Amino Acid Sequence
Amino acids 408 to 421 Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-ACADM antibody (
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Function This enzyme is specific for acyl chain lengths of 4 to 16.
Pathway Lipid metabolism; mitochondrial fatty acid beta-oxidation.
Involvement in disease Defects in ACADM are the cause of acyl-CoA dehydrogenase medium-chain deficiency (ACADMD) [MIM:201450]. It is an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy.
Sequence similarities Belongs to the acyl-CoA dehydrogenase family.
Cellular localization Mitochondrion matrix.
Information by UniProt
References for Human ACADM peptide (ab23229)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"