Human AFM exon 1 ChIP Primer and Probe Set (ab85778)

Overview

  • Product nameHuman AFM exon 1 ChIP Primer and Probe Set
  • Product overview

    Accession number: NM_001133.
    The HsAFM primers and probe can be used to quantify a control locus in chromatin immunoprecipitation (ChIP) assays with chromatin prepared from human cells.

    AFM (Alpha-albumin) is expressed in liver but inactive in most other cell types. The primers and probe are located in exon 1. In most cell types AFM is enriched with histone modifications associated with silencing (e.g. Histone H3 K27 di methylation, see image with ab24684). Whereas it shows low levels of histone modifications associated with active gene transcription such as Histone H3 K18 acetylation (see image with ab1191).

Properties

  • FunctionVitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient or across the blood-brain barrier.
  • Sequence similaritiesBelongs to the ALB/AFP/VDB family.
    Contains 3 albumin domains.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Alternative names
    • AFAM_HUMAN
    • Afamin
    • Afm
    • ALB 2
    • ALB2
    • ALBA
    • ALF
    • Alpha albumin
    • Alpha-Alb
    • Alpha-albumin
    see all

References for Human AFM exon 1 ChIP Primer and Probe Set (ab85778)

ab85778 has not yet been referenced specifically in any publications.

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We have tested some of our RNA polymerase II antibodies against both inactive genes and the 3' end of active genes. Below is a link to the antibodies.

http://www.abcam.com/RNA-polymerase-II-CTD-repeat-...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"