Human alpha smooth muscle Actin full length protein (ab134555)
- Product nameHuman alpha smooth muscle Actin full length proteinSee all alpha smooth muscle Actin proteins and peptides ...
- DescriptionRecombinant, His tag
- SourceE. coli
- Amino Acid Sequence
- SequenceMGSSHHHHHHSSGLVPRGSHMGSHMEEEDSTALVCDNGSG LCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVG DEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELR VAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVA IQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAI MRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEK LCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERF RCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYA NNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPER KYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
- Molecular weight44 kDa including tags
- Amino acids3 to 377
- TagsHis tag N-Terminus
Our Abpromise guarantee covers the use of ab134555 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Mass spectrometryMALDI-TOF
- Purity> 85
% by SDS-PAGE.
ab134555 is purified using conventional chromatography techniques.
- Concentration information loading...
Preparation and Storage
- Stability and Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 0.32% Tris HCl, 10% Glycerol, 0.88% Sodium chloride
- Actin alpha 2 smooth muscle aorta
- Actin aortic smooth muscle
- Actin, aortic smooth muscle
- Alpha 2 actin
- Alpha actin 2
- Alpha cardiac actin
- Cell growth inhibiting gene 46 protein
- Cell growth-inhibiting gene 46 protein
- Growth inhibiting gene 46
- FunctionActins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
- Involvement in diseaseDefects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
- Sequence similaritiesBelongs to the actin family.
- Cellular localizationCytoplasm > cytoskeleton.
References for Human alpha smooth muscle Actin full length protein (ab134555)
ab134555 has not yet been referenced specifically in any publications.