Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab39760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • ALS2 chromosome region gene 2
    • ALS2CR2
    • Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 2
    • Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein
    • CALS 21
    • CALS-21
    • ILP interacting protein ILPIPA
    • ILP-interacting protein
    • ILPIP
    • ILPIPA
    • Likely ortholog of mouse polyploidy associated protein kinase
    • PAPK
    • PRO1038
    • Pseudokinase ALS2CR2
    • STE20-related kinase adapter protein beta
    • STRAB_HUMAN
    • STRAD beta
    • STRADB
    see all
  • Function
    Pseudokinase which, in complex with CAB39, binds to and activates STK11. Relocates STK11 from the nucleus to the cytoplasm. Plays an essential role in STK11-mediated G1 cell cycle arrest.
  • Tissue specificity
    Highly expressed in heart, skeletal muscle, testis, liver and colon.
  • Sequence similarities
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
  • Domain
    The protein kinase domain is predicted to be catalytically inactive.
  • Cellular localization
    Nucleus. Cytoplasm.
  • Information by UniProt

References for Human ALS2CR2 peptide (ab39760)

ab39760 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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