Human Angiotensin II Type 1 Receptor peptide (ab91524)

Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceSSSAKKSASFFEVE
    • Amino acids346 to 359

Associated products

Specifications

Our Abpromise guarantee covers the use of ab91524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: PBS, BSA, pH 7.4

General Info

  • Alternative names
    • AG2S
    • Agtr 1
    • Agtr1
    • AGTR1_HUMAN
    • Agtr1a
    • AGTR1B
    • Ang II
    • Angiotensin II receptor type 1
    • Angiotensin II type-1 receptor
    • Angiotensin receptor 1
    • Angiotensin receptor 1B
    • AT 1B
    • AT 1r
    • AT1
    • At1a
    • AT1AR
    • AT1B
    • AT1BR
    • AT1R
    • AT2R1
    • AT2R1A
    • AT2R1B
    • HAT1R
    • Type 1 angiotensin II receptor
    • Type 1B angiotensin II receptor
    • Type-1 angiotensin II receptor
    see all
  • FunctionReceptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
  • Tissue specificityLiver, lung, adrenal and adrenocortical adenomas.
  • Involvement in diseaseDefects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    C-terminal Ser or Thr residues may be phosphorylated.
  • Cellular localizationCell membrane.
  • Information by UniProt

References for Human Angiotensin II Type 1 Receptor peptide (ab91524)

ab91524 has not yet been referenced specifically in any publications.

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The immunogen for ab31667 is a C-terminal fragment and does not overlap the peptide ab47407. Unfortunately, we do not currently sell any antibodies that can be used with the peptide ab47407.

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