Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceYPGYPPPPGGYPP-C
    • Amino acids3 to 15

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22983 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Annexin A11 antibody (ab4121)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • 56 kDa autoantigen
    • Annexin A11
    • Annexin XI
    • Annexin-11
    • AnnexinA11
    • AnnexinXI
    • ANX 11
    • ANX A11
    • ANX11
    • ANX11_HUMAN
    • ANXA 11
    • ANXA11
    • Autoantigen 56 kD
    • Calcyclin associated annexin 50
    • Calcyclin-associated annexin 50
    • CAP 50
    • CAP-50
    • CAP50
    • OTTHUMP00000059806
    see all
  • FunctionBinds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis.
  • Sequence similaritiesBelongs to the annexin family.
    Contains 4 annexin repeats.
  • DomainA pair of annexin repeats may form one binding site for calcium and phospholipid.
  • Cellular localizationCytoplasm. Melanosome. Nucleus envelope. Nucleus > nucleoplasm. Cytoplasm > cytoskeleton > spindle. Found throughout the nucleoplasm at interphase and during mitosis concentrates around the mitotic apparatus (By similarity). Elevation of intracellular calcium causes relocalization from the nucleoplasm to the nuclear envelope, with little effect on the cytoplasmic pool. Localization to the nuclear envelope is cell-cycle dependent.
  • Information by UniProt

References for Human Annexin A11 peptide (ab22983)

ab22983 has not yet been referenced specifically in any publications.

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