Overview

  • Product nameHuman APXL peptide

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceKCLLDSLQPERGK
    • Amino acids1604 to 1616

Specifications

Our Abpromise guarantee covers the use of ab23127 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • 4832440C16
    • Ab2-404
    • Apical like protein
    • Apical like protein APXL protein
    • apical protein of Xenopus-like
    • Apical protein Xenopus laevis like
    • apical protein, Xenopus laevis-like
    • apical protein-like
    • apical protein-like (Xenopus laevis)
    • Apical-like protein
    • APX homolog of Xenopus
    • C630003H05Rik
    • DKFZp781J074
    • FLJ39277
    • HSAPXL
    • Liver regeneration-related protein LRRG167
    • OTTHUMP00000022887
    • Protein Apxl
    • Protein Shroom2
    • Shrm2
    • SHRM2_HUMAN
    • SHROOM 2
    • Shroom family member 2
    • shroom2
    see all
  • FunctionMay be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution.
  • Tissue specificityAbundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas.
  • Sequence similaritiesBelongs to the shroom family.
    Contains 1 ASD1 domain.
    Contains 1 ASD2 domain.
    Contains 1 PDZ (DHR) domain.
  • DomainThe ASD1 domain mediates F-actin binding.
  • Cellular localizationApical cell membrane. Cell junction > tight junction. Cytoplasm > cytoskeleton. Associates with cortical F-actin.
  • Information by UniProt

References for Human APXL peptide (ab23127)

ab23127 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"