Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-NGVVTSIQDRYGS
    • Amino acids
      504 to 516

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22801 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-ARFGAP3 antibody (ab1308)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • ADP ribosylation factor GTPase activating protein 1
    • ADP ribosylation factor GTPase activating protein 3
    • ADP-ribosylation factor GTPase-activating protein 3
    • ARF GAP 3
    • ARFG3_HUMAN
    • ArfGAP 3
    • ARFGAP1
    • ARFGAP3
    • FLJ45618
    see all
  • Function
    GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
  • Tissue specificity
    Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.
  • Sequence similarities
    Contains 1 Arf-GAP domain.
  • Developmental stage
    Expressed at higher level in adult thymus, brain and lung, than in corresponding fetal tissues. Expressed at lower level in spleen, heart, kidney and liver during development.
  • Cellular localization
    Cytoplasm. Golgi apparatus membrane. Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
  • Information by UniProt

References

ab22801 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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