Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • AccessionP18848
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab24034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-ATF-4 antibody (ab23760)

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Activating transcription factor 4
    • ATF 4
    • ATF4
    • ATF4 protein
    • ATF4_HUMAN
    • cAMP-dependent transcription factor ATF-4
    • cAMP-responsive element-binding protein 2
    • CREB 2
    • CREB-2
    • CREB2
    • Cyclic AMP dependent transcription factor ATF 4
    • Cyclic AMP response element binding protein 2
    • Cyclic AMP-dependent transcription factor ATF-4
    • Cyclic AMP-responsive element-binding protein 2
    • DNA binding protein TAXREB67
    • DNA-binding protein TAXREB67
    • Tax Responsive Enhancer Element B67
    • Tax-responsive enhancer element-binding protein 67
    • TaxREB67
    • TXREB
    see all
  • FunctionTranscriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I.
  • Sequence similaritiesBelongs to the bZIP family.
    Contains 1 bZIP domain.
  • Cellular localizationCytoplasm. Cell membrane. Nucleus. Colocalizes with GABBR1 in hippocampal neuron dendritic membranes.
  • Information by UniProt

References for Human ATF-4 peptide (ab24034)

ab24034 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"