The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-BAI1 associated protein 2 isoform 3 antibody (ab791)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
BAI associated protein 2
Insulin receptor substrate p53
Insulin receptor substrate p53/p58
Insulin receptor substrate protein of 53 kDa
RelevanceBAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.
Cellular localizationCell Membrane and Cytoplasmic
References for Human BAI1 associated protein 2 isoform 3 peptide (ab19041)
has not yet been referenced specifically in any publications.
Publishing research using ab19041? Please let us know so that we can cite the reference in this datasheet.
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