Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceLQKYYCRVRGGRCAVLS
    • Amino acids6 to 22

Associated products

Specifications

Our Abpromise guarantee covers the use of ab42250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-beta Defensin 3 antibody [L3-18b-E1] (ab14422)

  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.1% Acetic acid

  • ReconstitutionResuspend in 0.1% acetic acid for required concentration. Store 2-8 °C (lyophilized)

General Info

  • Alternative names
    • BD 3
    • BD-3
    • BD3
    • beta 103
    • Beta defensin 103A
    • Beta defensin 103A precursor
    • Beta defensin 3
    • Beta-defensin 103
    • Beta-defensin 3
    • D103A_HUMAN
    • DEF B3
    • DEFB 103
    • DEFB 103A
    • DEFB 3
    • DEFB-3
    • DEFB103
    • DEFB103A
    • DEFB103B
    • DEFB3
    • Defensin
    • Defensin beta 103A
    • Defensin beta 3
    • Defensin like protein
    • Defensin-like protein
    • HBD 3
    • hBD-3
    • HBD3
    • HBP 3
    • HBP3
    • mBD3
    see all
  • FunctionExhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
  • Tissue specificityHighly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
  • Sequence similaritiesBelongs to the beta-defensin family.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Human beta Defensin 3 peptide (ab42250)

ab42250 has not yet been referenced specifically in any publications.

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