Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • AccessionO15540
    • SpeciesHuman
    • SequenceMKHHHHHHAS VEAFCATWKL TNSQNFDEYM KALGVGFATR QVGNVTKPTV IISQEGDKVV IRTLSTFKNT EISFQLGEEF DETTADDRNC KSVVSLDGDK LVHIQKWDGK ETNFVREIKD GKMVMTLTFG DVVAVRHYEK A
    • Molecular weight16 kDa including tags
    • Amino acids2 to 132
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab113868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Endotoxin level< 1.000 Eu/µg
  • Purity> 95 % by SDS-PAGE.
    Purity determined by densitometric image analysis
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituents: 99% Phosphate Buffer, 0.44% Sodium chloride

  • ReconstitutionAdd deionized water (200 µl) to prepare a working stock solution of approximately 0.5 mg/mL

General info

  • Alternative names
    • B FABP
    • B-FABP
    • BFABP
    • BLBP
    • Brain lipid binding protein
    • Brain lipid-binding protein
    • Brain-type fatty acid-binding protein
    • DKFZp547J2313
    • FABP 7
    • FABP7
    • FABP7_HUMAN
    • FABPB
    • Fatty Acid Binding Protein 7
    • Fatty acid binding protein 7 brain
    • Fatty acid binding protein brain
    • Fatty acid-binding protein 7
    • Fatty acid-binding protein, brain
    • Mammary derived growth inhibitor related
    • Mammary-derived growth inhibitor related
    • MRG
    • OTTHUMP00000017119
    see all
  • FunctionB-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers.
  • Tissue specificityExpressed in brain and other neural tissues.
  • Sequence similaritiesBelongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • DomainForms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
  • Cellular localizationCytoplasm.
  • Target information above from: UniProt accession O15540 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Human BLBP full length protein images

  • 14% SDS-PAGE separation of Human FABP7
    1. reduced and heated sample, 5µg/lane
    2. non-reduced and non-heated sample, 5µg/lane

References for Human BLBP full length protein (ab113868)

ab113868 has not yet been referenced specifically in any publications.

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