Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39780 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-CARD12 antibody (ab21301)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • and NACHT-containing protein
    • CARD
    • CARD 12
    • CARD LRR and NACHT containing protein
    • CARD LRR and NACHT containing protein 1
    • CARD12
    • Caspase recruitment domain containing protein 12
    • Caspase recruitment domain family member 12
    • Caspase recruitment domain-containing protein 12
    • CLAN
    • CLAN 1
    • CLAN A
    • CLAN B
    • CLAN C
    • CLAN D
    • Clan protein
    • CLAN1
    • CLANA
    • CLANB
    • CLANC
    • CLAND
    • CLR 2.1
    • CLR2.1
    • ICE protease activating factor
    • Ice protease-activating factor
    • Ipaf
    • LRR
    • NLR family CARD domain containing 4
    • NLR family CARD domain-containing protein 4
    • NLRC 4
    • NLRC4
    • NLRC4_HUMAN
    • NOD like receptor C4
    • Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 4
    • UNQ6189/PRO20215
    see all
  • FunctionPlays a role in the promotion of apoptosis.
  • Tissue specificityIsoform 2 is expressed ubiquitously, although highly expressed in lung and spleen. Isoform 1 is highly expressed in lung, followed by leukocytes especially monocytes, lymph node, colon, brain, prostate, placenta, spleen, bone marrow and fetal liver. Isoform 4 is only detected in brain.
  • Sequence similaritiesContains 1 CARD domain.
    Contains 14 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
  • Cellular localizationCytoplasm. Cytoplasmic filaments.
  • Information by UniProt

References for Human CARD12 peptide (ab39780)

ab39780 has not yet been referenced specifically in any publications.

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