Tumor up regulated CARD containing antagonist of CASP9
Tumor up regulated CARD containing antagonist of caspase 9
Tumor up-regulated CARD-containing antagonist of CASP9
tumor up-regulated CARD-containing antagonist of caspase nine
Tumor upregulated CARD containing antagonist of CASP9
FunctionInhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.
Tissue specificityHigh expression in lung, ovary, testis and placenta. Lower expression in heart, kidney and liver. Also expressed in spleen, lymph node and bone marrow.