Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    Blocking - Blocking peptide for Anti-CARD8 antibody (ab24186)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • Apoptotic protein NDPP 1
    • Apoptotic protein NDPP1
    • CARD 8
    • CARD inhibitor of NF kappa B activating ligand
    • CARD inhibitor of NF kappaB activating ligand
    • CARD inhibitor of NF kappaB activating ligands
    • CARD-inhibitor of NF-kappa-B-activating ligand
    • CARD8
    • CARD8_HUMAN
    • CARDINAL
    • Caspase recruitment domain containing protein 8
    • Caspase recruitment domain family member 8
    • Caspase recruitment domain protein 8
    • Caspase recruitment domain-containing protein 8
    • DACAR
    • Dakar
    • DKFZp779L0366
    • FLJ18119
    • FLJ18121
    • KIAA0955
    • MGC57162
    • NDPP
    • NDPP 1
    • NDPP1
    • TUCAN
    • Tumor up regulated CARD containing antagonist of CASP9
    • Tumor up regulated CARD containing antagonist of caspase 9
    • Tumor up-regulated CARD-containing antagonist of CASP9
    • tumor up-regulated CARD-containing antagonist of caspase nine
    • Tumor upregulated CARD containing antagonist of CASP9
    see all
  • FunctionInhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.
  • Tissue specificityHigh expression in lung, ovary, testis and placenta. Lower expression in heart, kidney and liver. Also expressed in spleen, lymph node and bone marrow.
  • Sequence similaritiesContains 1 CARD domain.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt

References for Human CARD8 peptide (ab39738)

ab39738 has not yet been referenced specifically in any publications.

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