Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceDRENTTGSDNTDTEGS amino acids 521 to 536 of human CARD9 (1).
    • Amino acids521 to 536

Associated products

Specifications

Our Abpromise guarantee covers the use of ab9650 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-CARD9 antibody (ab9649)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

General Info

  • Alternative names
    • CANDF2
    • CARD9
    • CARD9_HUMAN
    • Caspase recruitment domain family member 9
    • Caspase recruitment domain-containing protein 9
    • hCARD9
    see all
  • FunctionActivates NF-kappa-B via BCL10.
  • Tissue specificityHighly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
  • Involvement in diseaseDefects in CARD9 are the cause of familial candidiasis type 2 (CANDF2) [MIM:212050]. Chronic mucocutaneous candidiasis is characterized by impaired clearance of fungal infections and results in colonization and infections of the mucosa or skin, predominantly with Candida albicans. CANDF2 is an autosomal recessive chronic mucocutaneous candidiasis.
  • Sequence similaritiesContains 1 CARD domain.
  • Cellular localizationCytoplasm.
  • Information by UniProt

References for Human CARD9 peptide (ab9650)

ab9650 has not yet been referenced specifically in any publications.

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