Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      DRENTTGSDNTDTEGS amino acids 521 to 536 of human CARD9 (1).
    • Amino acids
      521 to 536

Associated products

Specifications

Our Abpromise guarantee covers the use of ab9650 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

General Info

  • Alternative names
    • CANDF2
    • CARD9
    • CARD9_HUMAN
    • Caspase recruitment domain family member 9
    • Caspase recruitment domain-containing protein 9
    • hCARD9
    see all
  • Function
    Activates NF-kappa-B via BCL10.
  • Tissue specificity
    Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
  • Involvement in disease
    Defects in CARD9 are the cause of familial candidiasis type 2 (CANDF2) [MIM:212050]. Chronic mucocutaneous candidiasis is characterized by impaired clearance of fungal infections and results in colonization and infections of the mucosa or skin, predominantly with Candida albicans. CANDF2 is an autosomal recessive chronic mucocutaneous candidiasis.
  • Sequence similarities
    Contains 1 CARD domain.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

References for Human CARD9 peptide (ab9650)

ab9650 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab9650.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up