Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-NRIKELTQSELEL
    • Amino acids
      348 to 360

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-CCNDBP1 antibody (ab15960)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • AU022347
    • CCDB1_HUMAN
    • CCNDBP 1
    • Ccndbp1
    • Cyclin D type binding protein 1
    • Cyclin-D1-binding protein 1
    • D type cyclin interacting protein 1
    • DIP 1
    • DIP1
    • GCIP
    • Grap 2 and cyclin D interacting protein
    • Grap 2 cyclin D interacting protein GCIP
    • Grap 2 cyclin interacting protein
    • Grap2 and cyclin D interacting protein
    • Grap2 and cyclin-D-interacting protein
    • Grap2 cyclin D interacting protein GCIP
    • Grap2 cyclin interacting protein
    • HHM
    • HHM protein
    • Human homolog of Maid
    • MAID
    • MAID protein
    • Maternal inhibition of differentiation
    • MGC109078
    • OTTMUSP00000017037
    • RP23 263D22.2
    • SECC 8
    • SSEC 8
    • Stage specific embryonic cDNA 8
    see all
  • Function
    May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
  • Tissue specificity
    Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
  • Sequence similarities
    Belongs to the CCNDBP1 family.
  • Developmental stage
    Expression may increase during differentiation.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

References

ab23288 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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