The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-CCNDBP1 antibody (ab15960)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Cyclin D type binding protein 1
Cyclin-D1-binding protein 1
D type cyclin interacting protein 1
Grap 2 and cyclin D interacting protein
Grap 2 cyclin D interacting protein GCIP
Grap 2 cyclin interacting protein
Grap2 and cyclin D interacting protein
Grap2 and cyclin-D-interacting protein
Grap2 cyclin D interacting protein GCIP
Grap2 cyclin interacting protein
Human homolog of Maid
Maternal inhibition of differentiation
Stage specific embryonic cDNA 8
FunctionMay negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
Tissue specificityUbiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
Sequence similaritiesBelongs to the CCNDBP1 family.
Developmental stageExpression may increase during differentiation.