Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab22407 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • C C chemokine receptor type 2
    • C C CKR 2
    • C-C chemokine receptor type 2
    • C-C CKR-2
    • CC chemokine receptor type 2
    • CC CKR 2
    • CC-CKR-2
    • CCCKR2
    • CCR 2
    • CCR-2
    • CCR1L
    • CCR2
    • CCR2_HUMAN
    • CCR2A
    • CCR2B
    • CCR5L
    • CD192
    • CD192 antigen
    • Chemokine C C motif receptor 2
    • Chemokine CC Motif Receptor 2
    • CKR 2
    • CKR2
    • CKR2A
    • CKR2B
    • CMKBR2
    • MCP 1 R
    • MCP-1-R
    • MCP1 RECEPTOR
    • MCP1R
    • Monocyte chemoattractant protein 1 receptor
    • Monocyte Chemotactic Protein 1 Receptor
    see all
  • FunctionReceptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationCell membrane.
  • Information by UniProt

References for Human CCR2 peptide (ab22407)

ab22407 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"