Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      EGTVFCLDPLDSRC
    • Amino acids
      291 to 304

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-CED6 antibody (ab2751)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • CED6
    • Cell death protein 6 homolog
    • Engulfment adapter protein
    • Engulfment adaptor PTB domain containing 1
    • GULP
    • GULP, engulfment adaptor PTB domain containing 1
    • GULP1
    • GULP1_HUMAN
    • Protein GULP
    • PTB domain adapter protein CED 6
    • PTB domain adapter protein CED-6
    • PTB domain adaptor protein CED6
    • PTB domain-containing engulfment adapter protein 1
    see all
  • Function
    May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
  • Tissue specificity
    Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.
  • Sequence similarities
    Belongs to the ced-6 family.
    Contains 1 PID domain.
  • Cellular localization
    Cytoplasm. May associate with the cytoplasmic side of the plasma membrane and early endosomes.
  • Information by UniProt

References

ab22934 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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