Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence 1
    • Species
      Human
    Amino Acid Sequence 2
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39745 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    Blocking - Blocking peptide for Anti-c-IAP1 and c-IAP2 antibody (ab25939)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • API 1
    • API1
    • Apoptosis inhibitor 1
    • Baculoviral IAP repeat containing 2
    • Baculoviral IAP repeat containing protein 2
    • Baculoviral IAP repeat-containing protein 2
    • BIRC 2
    • BIRC2
    • BIRC2_HUMAN
    • C IAP1
    • C-IAP1
    • cIAP 1
    • cIAP1
    • HIAP 2
    • HIAP-2
    • HIAP2
    • IAP 2
    • IAP homolog B
    • IAP-2
    • IAP2
    • Inhibitor of apoptosis protein 2
    • MIHB
    • NFR2 TRAF signalling complex protein
    • RING finger protein 48
    • RNF 48
    • RNF48
    • TNFR2 TRAF signaling complex protein 2
    • TNFR2-TRAF-signaling complex protein 2
    see all
  • Function
    Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
  • Tissue specificity
    Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.
  • Sequence similarities
    Belongs to the IAP family.
    Contains 3 BIR repeats.
    Contains 1 CARD domain.
    Contains 1 RING-type zinc finger.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

References

ab39745 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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