Human CLNS1A protein fragment (ab91674)
- Product nameHuman CLNS1A protein fragmentSee all CLNS1A proteins and peptides ...
- SourceE. coli
- Amino Acid Sequence
- SequenceESRLSWLDGSGLGFSLEYPTISLHALSRDRSDCLGEHLYV MVNAKFE EESKEPVADEEEEDSDDDVEPITEFRFVPSD KSALEAMFTAMCECQA LHPDPEDEDSDDYDGEEYDVEA HEQGQGDIPTFYTYEEGLSHLTAEG QATLERLEGMLSQ SVSSQYNMAGVRTEDSIRDYEDGMEVDTTPTVAG QFED ADVDH
- Amino acids41 to 237
Our Abpromise guarantee covers the use of ab91674 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Additional NotesProtein Identity confirmed by Mass Spectrometry (MS/MS) (acquired on initial reference batch).
- Concentration information loading...
Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
- ReconstitutionReconstitute with 148 µl aqua dest.
- Chloride channel
- Chloride channel nucleotide sensitive 1A
- Chloride channel regulatory protein
- Chloride conductance regulatory protein ICln
- Chloride ion current inducer protein
- CLNS 1A
- Methylosome subunit pICln
- nucleotide sensitive 1A
- Reticulocyte pICln
- FunctionThe interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway.
- Sequence similaritiesBelongs to the pICln family.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
- Cellular localizationCytoplasm. Nucleus. Cytoplasm > cytoskeleton. A small fraction is also associated with the cytoskeleton.
Human CLNS1A protein fragment images
The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.
References for Human CLNS1A protein fragment (ab91674)
ab91674 has not yet been referenced specifically in any publications.