- Datasheet
- Specific References
- Protocols
Overview
- Product nameHuman Cofilin peptide
See all Cofilin proteins and peptides
Description
- NatureSynthetic
- Amino Acid Sequence
- SpeciesHuman
Associated products
- Corresponding Antibody
Specifications
Our Abpromise guarantee covers the use of ab37634 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Applications
ELISA
Western blot
Blocking - Blocking peptide for Anti-Cofilin antibody (ab29038)
- FormLiquid
-
Concentration information loading...
Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.05% Sodium Azide
Constituents: PBS
General Info
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Alternative names
- 18 kDa phosphoprotein
- CFL
- CFL 1
see all - FunctionControls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
- Tissue specificityWidely distributed in various tissues.
- Sequence similaritiesBelongs to the actin-binding proteins ADF family.
Contains 1 ADF-H domain. - Post-translational
modificationsPhosphorylated on Ser-3 in resting cells. - Cellular localizationNucleus matrix. Cytoplasm > cytoskeleton. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.
- Information by UniProt
References for Human Cofilin peptide (ab37634)
ab37634 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"