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- Amino Acid Sequence
- Amino acids438 to 450
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-CSK antibody (ab744)
Concentration information loading...
Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- C SRC
- C SRC kinase
- C src Tyrosine Kinase
- FunctionSpecifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.
- Tissue specificityExpressed in lung and macrophages.
- Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
Contains 1 protein kinase domain.
Contains 1 SH2 domain.
Contains 1 SH3 domain.
modificationsAutophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.
- Cellular localizationCytoplasm. Cell membrane. Mainly cytoplasmic, also present in lipid rafts.
Information by UniProt
References for Human CSK peptide (ab19039)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"