Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab46217 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-CXCR5 antibody (ab46218)

  • Form
    Liquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • BLR 1
    • BLR1
    • Burkitt lymphoma receptor 1
    • Burkitt lymphoma receptor 1 GTP binding protein
    • Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)
    • C X C chemokine receptor type 5
    • C-X-C chemokine receptor type 5
    • CD 185
    • CD185
    • CD185 antigen
    • Chemokine (C-X-C motif) receptor 5
    • Chemokine C X C motif receptor 5
    • Chemokine CXC motif receptor 5
    • Chemokine receptor 5
    • CXC chemokine receptor type 5
    • CXC R5
    • CXC-R5
    • CXCR 5
    • CXCR-5
    • Cxcr5
    • CXCR5_HUMAN
    • MDR 15
    • MDR-15
    • MDR15
    • MGC117347
    • Monocyte derived receptor 15
    • Monocyte-derived receptor 15
    see all
  • Function
    Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.
  • Tissue specificity
    Expression in mature B-cells and Burkitt lymphoma cells.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

References

ab46217 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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