Human Cystatin C peptide (ab68289)
- Product nameHuman Cystatin C peptideSee all Cystatin C proteins and peptides ...
Our Abpromise guarantee covers the use of ab68289 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Purity70 - 90% by HPLC.
- Concentration information loading...
Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
- AD 8
- Amyloid angiopathy and cerebral hemorrhage
- bA218C14.4 (cystatin C)
- Cst 3
- CST3 protein
- Cystatin 3
- Gamma trace
- Neuroendocrine basic polypeptide
- Post gamma globulin
- FunctionAs an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
- Tissue specificityExpressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
- Involvement in diseaseAmyloidosis 6
Age-related macular degeneration 11
- Sequence similaritiesBelongs to the cystatin family.
modificationsThe Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21.
- Cellular localizationSecreted.
References for Human Cystatin C peptide (ab68289)
ab68289 has not yet been referenced specifically in any publications.