Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-SEMYRDPFGNPFA
    • Amino acids758 to 770

Specifications

Our Abpromise guarantee covers the use of ab45512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General info

  • Alternative names
    • DAB 2
    • Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
    • DAB2
    • Differentially expressed in ovarian cancer 2
    • Differentially expressed protein 2
    • Disabled (Drosophila) homolog 2 (mitogen responsive phosphoprotein)
    • disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein)
    • Disabled homolog 2
    • Disabled homolog 2 mitogen responsive phosphoprotein
    • Disabled homolog 2 mitogen responsive phosphoprotein (Drosophila)
    • disabled homolog 2 mitogen-responsive phosphoprotein (Drosophila)
    • Disabled, Drosophila, homolog of, 2
    • DOC 2
    • DOC2
    • FLJ26626
    • Mitogen responsive phosphoprotein
    see all
  • RelevanceDAB2 is a component of the CSF1 signal transduction pathway. DAB2 mRNA is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines. The down regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2 like domains, alpha and beta).
  • Cellular localizationCytoplasmic vesicle; clathrin coated vesicle; clathrin coated vesicle membrane. Cell membrane; coated pit; clathrin coated pit. Note: Colocalizes with large insert containing isoforms of MYO6 at clathrin coated pits/vesicles.

References for Human DAB2 peptide (ab45512)

ab45512 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab45512.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"