Human Dact1 / Dapper homolog 1 peptide (ab42546)

Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab42546 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General info

  • Alternative names
    • Dact
    • Dact1
    • DACT1_HUMAN
    • Dapper
    • Dapper antagonist of beta catenin homolog 1
    • Dapper antagonist of catenin 1
    • Dapper homolog 1
    • DAPPER1
    • Dpr
    • Dpr1
    • Frd
    • Frodo
    • hDPR1
    • Hepatocellular carcinoma novel gene 3 protein
    • Heptacellular carcinoma novel gene 3
    • HNG3
    • MTNG3
    • Thyex3
    see all
  • FunctionPositively regulates DVL2-mediated signaling pathways during development. Binds to DVL2 and impedes the degradation of CTNNB1/beta-catenin, thereby enhancing the transcriptional activation of target genes of the Wnt signaling pathway.
  • Sequence similaritiesBelongs to the dapper family.
  • DomainThe C-terminal PDZ-binding motif mediates interaction with the PDZ domains of DSH (Dishevelled) family proteins.
  • Cellular localizationCytoplasm. Nucleus.
  • Target information above from: UniProt accession Q9NYF0 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for Human Dact1 / Dapper homolog 1 peptide (ab42546)

ab42546 has not yet been referenced specifically in any publications.

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